In-Depth Guide

Stem Cells

Procuring, Culturing, and Working with Nature’s Life Supply

As the life source of the entire hematopoietic system, stem cells hold immense — and still largely untapped — power for our understanding of the human immune system and regenerative medicine.

For researchers, stem cells hold just as many questions as answers, if not more. Before working with stem cells, browse some of our best resources to expand your knowledge of these life-giving cells, including how you can get them, the best types for your area of study, and tips for working with mouse models.

By Anne Lodge, Ph.D.

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Consider the Source (Blog Post)


You might know that CD34+ stem cells can be sourced from three different locations: bone marrow, cord blood, and peripheral blood. But does it matter which source you use for your CD34+ cells? And do you know the different functions and best use cases for each?

Learn when and why you should get CD34+ stem cells from bone marrow, cord blood, or peripheral blood.

Learn More
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What’s the Difference Between Progenitor and CD34+ Cells? (Blog Post)

Stem Cells FlowchartProgenitor cells and CD34+ cells are often referred to interchangeably as stem cells. While this oversimplification is technically correct, there are many distinctions between the origins, functions, and uses of progenitor cells and CD34+ cells.

Despite their many similarities, the most significant difference between the two cell types is that progenitor cells have a limited number of divisions, while CD34+ cells can divide and replicate indefinitely.

Explore
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Advantages of Mobilized Stem Cells vs. Bone Marrow Stem Cells (Blog Post)

In the nearly 65 years since the first successful bone marrow transplant, there have been immense leaps forward in both stem cell sourcing processes and technologies. Today, mobilized CD34+ stem cells offer several advantages over stem cells derived from bone marrow and other sources.

Learn more about the history of stem cell sourcing and the advantages of mobilized CD34+ cells.

See the Difference
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How to Thaw Cells (Protocol)

In this simple procedure, speed is key to maximum cell recovery.

Get Thawing Tips
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Publications Featuring Cellero Cells (Research Articles)

Journal articles and discoveries using our stem cell products.

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Human Stem Cells for Research (Products)

Large batches in stock ready for overnight shipping. Normal CD34+, Mobilized CD34+, and Cord Blood Mononuclear Cells.

Browse All Stem Cells
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Save Time with Ready-to-Use Mast Cells (Blog Post)

If you use mast cells for allergy or inflammation research, you have undoubtedly wasted time procuring stem cells or bone marrow cells from a specific human or mouse donor, adding the right protein and growth factor, culturing, and incubating before finally collecting the mast cells 2–3 weeks later. All before you could even start using the cells you needed!

Skip the culture and get the cells you need, ready to thaw and use.

Mouse Cells Without the Mess
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Mouse Bone Marrow: Your Multipurpose Cells (Blog Post)

Mouse bone marrow cells are a multipurpose resource for conversion to several other useful cell types. Mouse bone marrow contains hematopoietic stem cells, which makes it an excellent starting point for deriving cells of various hematopoietic lineages.

Learn how to convert mouse bone marrow cells into three other cell types.

Get Started
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Culture of Mouse Bone Marrow Cells (Protocol)

Materials, procedures, and special research notes.

See Instructions
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Browse Mouse Bone Marrow Cells (Products)

The potential to generate all hematopoietic cell types.

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