Scientists choose Cellero’s cells for quality and reliability. View the published research and patent applications below to learn how scientists like you are using our products in their research.
Note that some publications may refer to Astarte Biologics, Cellero’s previous name.
CUE-101, a novel HPV16 E7-pHLA-IL-2-Fc fusion protein, enhances tumor antigen specific T cell activation for the treatment of HPV16-driven malignancies. Clinical Cancer Research. 2020.
Therapeutic SIRP-alpha antibodies. 2020.
A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB Journal. 2020.
Feasibility, potency, and safety of growing human mesenchymal stem cells in space for clinical application. Microgravity. 2020.
T cells with reduced surface fucosylation and methods of making and using the same. 2020.
Anti-TIGIT antigen-binding proteins and methods thereof. 2020.
DNA-mediated assembly of multispecific antibodies for T cell engaging and tumor killing. Advanced Science. 2019.
Bispecific fusion polypeptides and methods of use thereof. 2019.
T-Scan: A genome-wide method for the systematic discovery of T cell epitopes. Cell. 2019.
Effect of comedications and endotoxins on mesenchymal stem cell secretomes, migratory and immunomodulatory capacity. Journal of Clinical Medicine. 2019.
Modulators of zinc activated cation channel. 2019.
Antibodies that specifically bind PD-1 and methods of use. 2018.
Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release. Journal of Controlled Release. 2018.
Bispecific SCFV Immunofusion (BIF). 2018.
Modified IL-2 variants that selectively activate regulatory T cells. 2018.
Monocyte function in patients with myelodysplastic syndrome. Journal of Leukocyte Biology. 2018.
Gene array analysis of PD-1H overexpressing monocytes reveals a pro-inflammatory profile. Heliyon. 2018.
Anti-TIGIT antigen-binding proteins and methods of use thereof. 2017.
TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells. Journal of Leukocyte Biology. 2017.
A DNA vaccine protects human immune cells against Zika Virus infection in humanized mice. EBioMedicine. 2017.
Natural killer T cell-targeted immunotherapy mediating long-term memory responses and strong antitumor activity. Frontiers in Immunology. 2017.
PTHrP (12-48) modulates the bone marrow microenvironment and suppresses human osteoclast differentiation and lifespan. Journal of Bone and Mineral Research. 2017.
Dosage and administration of non-fucosylated anti-CD40 antibodies. 2017.
Hepatitis C virus upregulates B-cell receptor signaling: A novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. 2015.
Pharmaceutical compounds targeted by MIF affinity-tethered moieties. 2015.
Human monoclonal antibodies to programmed death ligand 1 (PD-L1). 2015.
In vitro characterization of the anti-PD-1 antibody Nivolumab, BMS-936558, and in vivo toxicology in non-human primates. Cancer Immunology Research. 2014.
Follicular lymphoma-protective HLA class II variants correlate with increased HLA-DQB1 protein expression. Genes and Immunity. 2013
Gadolinium contrast agent-induced CD163+ ferroportin+ osteogenic cells in nephrogenic systemic fibrosis. American Journal of Pathology. 2013.
The design, selection, and evaluation of highly specific and functional siRNA incorporating unlocked nucleobase analogs. Methods in Molecular Biology. 2013.
cDNA normalization by hydroxyapatite chromatography to enrich transcriptome diversity in RNA-seq applications. BioTechniques. 2012.
LXR-mediated inhibition of CD4+ T helper cells. PLOS ONE. 2012.
Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells. Protein Engineering Design and Selection. 2012.
HIV-1 co-infection and morphine co-exposure severely dysregulate HCV-induced hepatic pro-inflamatory cytokine release and free radical production: Increased pathogenesis coincides with uncoordinated host-defenses. Journal of Virology. 2011.
PLTP regulates STAT3 and NFκB in Differentiated THP-1 cells and human monocyte-derived macrophages. Biochimica et Biophysica Acta (BBA). 2011.
Potent and systematic RNAi mediated silencing with single oligonucleotide compounds. RNA. 2011.
Iron chelators of the DpT and BpT series inhibit HIV-1 transcription: Identification of novel cellular targets — Iron, CDK2 and CDK9. Molecular Pharmacology. 2010.
Novel adenovirus vectors “capsid-displaying” a human complement inhibitor. Journal of Innate Immunity. 2010.
Novel cancer vaccine based on genes of Salmonella pathogenicity island 2. International Journal of Cancer. 2010.
Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. Journal of Clinical Investigation. 2009.
A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of β-catenin/GSK3 signaling. PLOS ONE. 2009.
Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma. Journal of Clinical Investigation. 2007.
Chemical functionalization of PEG-b-PPS nanocarriers for applications in targeted and sustained delivery. ProQuest Dissertations Publishing. 2019.
Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages. Traffic. 2018.
Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα signaling. Biochemical Journal. 2018.
Crown-like structures as a biomarker for cancer risk and cancer prognosis. 2013.
Identification of palmitoyl protein thioesterase 1 in human THP-1 monocytes/macrophages and characterization of unique biochemical activities for this enzyme. Biochemistry. 2013.
Transcriptional profiling and pathway analysis of CSF-1 and IL-34 effects on human monocyte differentiation. Cytokine. 2013.
Activating mutations in β-Catenin in colon cancer cells alter their interaction with macrophages; the role of snail. PLOS ONE. 2012.
NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against Gram-negative bacterial infection. Journal of Immunology. 2012.
Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women. Cancer Discovery. 2012.
Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques. Journal of the American College of Cardiology. 2011.
Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prevention Research. 2011.
Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 2010.
The EBV-encoded dUTPase activates NF-kB through the TLR2 and MyD88-dependent signaling pathway. Journal of Immunology. 2009.
The NF-kB/AKT-dependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1B. Cancer Microenvironment. 2009.
Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: A crosstalk interrupted by vitamin D3. Oncogene. 2009.
Systematic identification of novel SLE related autoantibodies responsible for Type I IFN production in human plasmacytoid dendritic cells. Cellular Immunology. 2013.
S-layer associated proteins contribute to the adhesive and immunomodulatory properties of Lactobacillus acidophilus NCFM. BMC Microbiology. 2020.
Adaptor protein-1 (AP-1) promotes cross-presentation through the same tyrosine signal in MHC-I that is targeted by HIV-1. Journal of Virology. 2013.
Negatively charged liposomes show potent adjuvant activity when simply admixed with protein antigens. Molecular Pharmaceutics. 2011.
Adaptor protein-1 (AP-1) promotes cross-presentation through the same tyrosine signal in MHC-I that is targeted by HIV-1. Journal of Virology. 2013.
The Yersinia pestis GTPase BipA promotes pathogenesis of primary pneumonic plague. Infection and Immunity. 2020.
Inducible expression of a disease-associated ELANE mutation impairs granulocytic differentiation, without eliciting an unfolded protein response. Journal of Biological Chemistry. 2020.
DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes. PLOS Pathogens. 2019.
Antibodies that bind peptidoglycan recognition protein 1. 2018.
Increased mortality in mice following immunoprophylaxis therapy with high 2 dosage of nicotinamide in Burkholderia persistent infections. Infection and Immunity. 2018.
Therapeutic SIRP-alpha antibodies. 2020.
Epstein-Barr Virus dUTPase induces neuroinflammatory mediators: Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Clinical Therapeutics. 2019.
DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes. Cell Death & Disease. 2020.
Botulinum toxin blocks mast cells and prevents rosacea like inflammation. Journal of Dermatological Science. 2018.
Effects of opioid and nonopioid analgesics on canine wheal formation and cultured human mast cell degranulation. Toxicology and Applied Pharmacology. 2017.
CUE-101, a novel HPV16 E7-pHLA-IL-2-Fc fusion protein, enhances tumor antigen specific T cell activation for the treatment of HPV16-driven malignancies. Clinical Cancer Research. 2020.
Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors. 2020.
Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway. Scientific Reports. 2020.
Methods and systems for processing polynucleotides. 2020.
Anti-CD112R compositions and methods. 2020.
Rapid production of physiologic dendritic cells (phDC) for immunotherapy. Cell Reprogramming for Immunotherapy. 2019.
Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains. 2019.
Cancer treatment using 2-deoxy-2-fluoro-L-fucose in combination with a checkpoint inhibitor. 2018.
Checkpoint regulator antagonists. 2018.
Generation and analysis of human T cell lines responsive to Glatiramer Acetate. Cell Reports. 2018.
Preventing cytokine release syndrome. 2020.
Therapeutic SIRP-alpha antibodies. 2020.
Intracellular delivery using microfluidics-assisted cell screening (macs). 2020.
Multimeric GITR binding molecules and uses thereof. 2019.
Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation. Scientific Reports. 2018.
Automated expansion of primary human T cells in scalable and cell‐friendly hydrogel microtubes for adoptive immunotherapy. Advanced Healthcare Materials. 2018.
An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides. Journal for ImmunoTherapy of Cancer. 2018.
MNK controls mTORC1:substrate association through regulation of TELO2 binding with mTORC1. Cell Reports. 2017.
Modulating the immune response using antibody-drug conjugates. 2020.
Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases. 2020.
Analytical performance of an immunoprofiling assay based on RNA models. The Journal of Molecular Diagnostics. 2020.
Metabolic rewiring in response to biguanides is mediated by mROS/HIF-1a in malignant lymphocytes. Cell Reports. 2019.
Multimeric GITR binding molecules and uses thereof. 2019.
Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases. 2019.
Quantifying CD4 receptor density on human T lymphocytes using multiple reaction monitoring mass spectrometry. Analytical Chemistry. 2013.
Secretable variant immunomodulatory proteins and engineered cell therapy. 2020.
Tunable variant immunoglobulin superfamily domains and engineered cell therapy. 2018.
Immunomodulatory proteins with tunable affinities. 2018.
ICOS ligand variant immunomodulatory proteins and uses thereof. 2017.
Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis. Journal of Immunology. 2013.
Therapeutic SIRP-alpha antibodies. 2020.
Regulatory T cell epitopes. 2020.
OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor activity. Journal of Clinical Investigation. 2020.
Anti-PD-1 antibodies and therapeutic uses thereof. 2018.
Antibodies to human programmed death receptor PD-1. 2018.
Antibodies to TIGIT. 2017.
Hybrid hyaluronic acid hydrogel/poly (ε‐caprolactone) scaffold provides mechanically favorable platform for cartilage tissue engineering studies. Journal of Biomedical Materials Research Part A. 2013.