Scientists choose Cellero’s cells for quality and reliability. View the published research and patent applications below to learn how scientists like you are using our products in their research.

Note that some publications may refer to Astarte Biologics, Cellero’s previous name.

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PBMC

CUE-101, a novel HPV16 E7-pHLA-IL-2-Fc fusion protein, enhances tumor antigen specific T cell activation for the treatment of HPV16-driven malignancies. Clinical Cancer Research. 2020.

Therapeutic SIRP-alpha antibodies. 2020.

A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB Journal. 2020.

Feasibility, potency, and safety of growing human mesenchymal stem cells in space for clinical application. Microgravity. 2020.

T cells with reduced surface fucosylation and methods of making and using the same. 2020.

Anti-TIGIT antigen-binding proteins and methods thereof. 2020.

DNA-mediated assembly of multispecific antibodies for T cell engaging and tumor killing. Advanced Science. 2019.

Bispecific fusion polypeptides and methods of use thereof. 2019.

T-Scan: A genome-wide method for the systematic discovery of T cell epitopes. Cell. 2019.

Effect of comedications and endotoxins on mesenchymal stem cell secretomes, migratory and immunomodulatory capacity. Journal of Clinical Medicine. 2019.

Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function. PLOS Pathogens. 2019.

Selective expansion of different subpopulations of T cells by the alteration of cell surfacing signals and signal ratio. 2019.

Modulators of zinc activated cation channel. 2019.

Antibodies that specifically bind PD-1 and methods of use. 2018.

Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release. Journal of Controlled Release. 2018.

Bispecific SCFV Immunofusion (BIF). 2018.

Modified IL-2 variants that selectively activate regulatory T cells. 2018.

Monocyte function in patients with myelodysplastic syndrome. Journal of Leukocyte Biology. 2018.

Gene array analysis of PD-1H overexpressing monocytes reveals a pro-inflammatory profile. Heliyon. 2018.

Anti-TIGIT antigen-binding proteins and methods of use thereof. 2017.

TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells. Journal of Leukocyte Biology. 2017.

A DNA vaccine protects human immune cells against Zika Virus infection in humanized mice. EBioMedicine. 2017.

Natural killer T cell-targeted immunotherapy mediating long-term memory responses and strong antitumor activity. Frontiers in Immunology. 2017.

PTHrP (12-48) modulates the bone marrow microenvironment and suppresses human osteoclast differentiation and lifespan. Journal of Bone and Mineral Research. 2017.

Dosage and administration of non-fucosylated anti-CD40 antibodies. 2017.

Hepatitis C virus upregulates B-cell receptor signaling: A novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. 2015.

Pharmaceutical compounds targeted by MIF affinity-tethered moieties. 2015.

Human monoclonal antibodies to programmed death ligand 1 (PD-L1). 2015.

In vitro characterization of the anti-PD-1 antibody Nivolumab, BMS-936558, and in vivo toxicology in non-human primates. Cancer Immunology Research. 2014.

Follicular lymphoma-protective HLA class II variants correlate with increased HLA-DQB1 protein expression. Genes and Immunity. 2013

Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cells. PLOS ONE. 2013.

Gadolinium contrast agent-induced CD163+ ferroportin+ osteogenic cells in nephrogenic systemic fibrosis. American Journal of Pathology. 2013.

The design, selection, and evaluation of highly specific and functional siRNA incorporating unlocked nucleobase analogs. Methods in Molecular Biology. 2013.

cDNA normalization by hydroxyapatite chromatography to enrich transcriptome diversity in RNA-seq applications. BioTechniques. 2012.

LXR-mediated inhibition of CD4+ T helper cells. PLOS ONE. 2012.

Engineering a CD123xCD3 bispecific scFv immunofusion for the treatment of leukemia and elimination of leukemia stem cells. Protein Engineering Design and Selection. 2012.

HIV-1 co-infection and morphine co-exposure severely dysregulate HCV-induced hepatic pro-inflamatory cytokine release and free radical production: Increased pathogenesis coincides with uncoordinated host-defenses. Journal of Virology. 2011.

PLTP regulates STAT3 and NFκB in Differentiated THP-1 cells and human monocyte-derived macrophages. Biochimica et Biophysica Acta (BBA). 2011.

Potent and systematic RNAi mediated silencing with single oligonucleotide compounds. RNA. 2011.

Iron chelators of the DpT and BpT series inhibit HIV-1 transcription: Identification of novel cellular targets — Iron, CDK2 and CDK9. Molecular Pharmacology. 2010.

Novel adenovirus vectors “capsid-displaying” a human complement inhibitor. Journal of Innate Immunity. 2010.

Novel cancer vaccine based on genes of Salmonella pathogenicity island 2. International Journal of Cancer. 2010.

Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. Journal of Clinical Investigation. 2009.

A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of β-catenin/GSK3 signaling. PLOS ONE. 2009.

Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma. Journal of Clinical Investigation. 2007.

Monocytes

Chemical functionalization of PEG-b-PPS nanocarriers for applications in targeted and sustained delivery. ProQuest Dissertations Publishing. 2019.

Phagocytosis of antibody-opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages. Traffic. 2018.

Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXRα signaling. Biochemical Journal. 2018.

Crown-like structures as a biomarker for cancer risk and cancer prognosis. 2013.

Identification of palmitoyl protein thioesterase 1 in human THP-1 monocytes/macrophages and characterization of unique biochemical activities for this enzyme. Biochemistry. 2013.

Transcriptional profiling and pathway analysis of CSF-1 and IL-34 effects on human monocyte differentiation. Cytokine. 2013.

Activating mutations in β-Catenin in colon cancer cells alter their interaction with macrophages; the role of snail. PLOS ONE. 2012.

NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against Gram-negative bacterial infection. Journal of Immunology. 2012.

Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women. Cancer Discovery. 2012.

Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques. Journal of the American College of Cardiology. 2011.

Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prevention Research. 2011.

Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 2010.

Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of snail in tumor cells. PLOS ONE. 2010.

The EBV-encoded dUTPase activates NF-kB through the TLR2 and MyD88-dependent signaling pathway. Journal of Immunology. 2009.

The NF-kB/AKT-dependent induction of Wnt signaling in colon cancer cells by macrophages and IL-1B. Cancer Microenvironment. 2009.

Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: A crosstalk interrupted by vitamin D3. Oncogene. 2009.