Tetanus Toxoid Specific T Cells
|Blood Type :||ONeg|
|Donor Health :||Healthy|
|HLA-DRβ 1 :||11,01|
Additional Donor Information:
These CD4+ T cells are specific for a peptide (QYIKANSKFIGITEL) derived from tetanus toxoid bound to HLA-DRB1*01. They also recognize whole tetanus toxoid but only when presented by dendritic cells, not B-LCL.
The T cells proliferate when stimulated with antigen and APC. They also produce IFNg, IL-5, IL-10, and IL-13.
Healthy female donor, CMV negative. 5′ 10″ tall, 210 lbs. Her genotype at Fc gamma RIII alpha 158 is F/V.
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