Anti-HPV E7(82-90) T Cells
| Donor #: | 224 |
|---|---|
| Size: | 1-2M cells/vial |
| Price: | $ 550.00 |
| In Stock: | 52 |
| Need More? | |
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Donor Details
| Blood Type : | BNeg |
|---|---|
| Age : | 55 |
| Gender : | Female |
| Ethnicity : | Caucasian |
| Anticoagulant : | Unknown |
| HLA-A : | 02:01,02:01 |
| HLA-B : | 07,15 |
| HLA-C : | 03,07 |
| HLA-DRβ 1 : | 15,13 |
| CMV : | Positive |
Additional Donor Information:
T cell population reactive to an HLA-A0201-restricted HPV E7 peptide from position 82-90 (LLMGTLGIV)
This donor is CMV positive and Fc gamma RIIIa F/F. She is 5′ 3″ tall and weighs 180 lbs.
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About Antigen-Specific T Cells
Antigen-specific T cells are unique tools for studying the immune system. The T cell receptor is, like immunoglobulin, generated by genetic rearrangement of multiple gene segments. This rearrangement creates an army of T cells, each directed against a unique peptide antigen.
The T cell repertoire responds to viruses, bacteria, tumor cells and, in the case of autoimmune disease, peptides derived from normal tissues. Each peptide specificity is only found in a small fraction of circulating T cells, making study of antigen-specific reactions difficult.
We have developed T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.