Anti-HSV T cells ASTC, 1-2M cells New

Donor #: 358
Size: 1-2M cells/vial
Price: $600.00
In Stock: 38
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Donor Details

Blood Type : OPos
Age : 52
Gender : Female
Ethnicity : Caucasian
HLA-A : 02:01,02:01
HLA-B : 44:02,15:01
HLA-C : 03:03,05:01
HLA-DRβ 1 : 01:03,04:04
CMV : Negative

Additional Donor Information:

These T cells recognize a peptide from glycoprotein D1 [gD1(53-61): SLPITVYYA] of Herpes simplex virus (HSV) presented by HLA-A*0201.

Donor is 5′ 6″ tall and weighs 230 lbs. She has allergies to sulfa drugs and takes Synthroid for thyroid problem. She is F/F at Fc gamma RIII alpha 158.

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About Antigen-Specific T Cells

Antigen-specific T cells are unique tools for studying the immune system. The T cell receptor is, like immunoglobulin, generated by genetic rearrangement of multiple gene segments. This rearrangement creates an army of T cells, each directed against a unique peptide antigen.

The T cell repertoire responds to viruses, bacteria, tumor cells and, in the case of autoimmune disease, peptides derived from normal tissues. Each peptide specificity is only found in a small fraction of circulating T cells, making study of antigen-specific reactions difficult.

We have developed T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.