Cellosaurus is a comprehensive online knowledge base that attempts to list and describe all known cell lines used in biomedical research. It features immortalized, naturally immortal, and finite life cell lines for vertebrates and invertebrates, but does not include primary cell lines or plant cell lines.

 

Why We Love Cellosaurus

1. If you want to learn anything about a cell line, Cellosaurus is probably the best place to start. As of October 2020, the database contains 124,000+ cell lines!

Each listing includes the recommended cell line name, synonyms, an accession number, species, contaminated/misidentified lines, HLA typing, disease entry codes, parent lines, gender, age, publication references, and much more.

 

2. They take careful consideration to pull in relevant publications related to each cell line, including the original publications.

 

3. HLA typing is critical to so many research endeavors, and Cellosaurus doesn’t skimp here. They provide HLA types for most lines.

 

4. They have a new SARS-CoV-2 resource that contains cell lines that have been used to grow SARS-CoV-2, those not suitable to grow SARS-CoV-2, cellular vaccine lines, and hybridomas.

 

An example cell line listing accessed from Cellosaurus in December 2020.

 

How to Use Cellosaurus

The database is very user-friendly, and there are multiple ways to access the information you’re looking for:

  • Search by cell line name or try searching for a tumor antigen or cell type — it’s amazing what you can find!
  • Browse by cell line group (e.g., cancer stem cell lines, bird cell lines, human/rodent somatic cell hybrids)
  • Browse by cell line panel (e.g., 10IHW cell line panel, 4AOHW cell line panel, COSMIC cell lines project)
  • Browse problematic cell lines (those that are contaminated or misidentified)
  • CLASTR STR similarity search
  • Download databases in various formats

 

Questions About Cellosaurus?

Visit their frequently asked questions to learn more. If you’re facing a research roadblock, our expert team of researchers is always available to help!

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