There is a new method for discovering T cell epitopes, recently detailed in a Cell article, T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes. T cell profiling technologies have long been a limitation to our understanding of T cell antigens, something that the creators of T-Scan hope to address. How T-Scan…
The Allele Frequency Net Database (AFND) is a free online resource that compiles known allele frequencies from different polymorphic areas of the human genome into one searchable database. The online database currently holds information from over 1,600 population studies with frequencies from more than 10.5 million individuals. Frequencies are included from several immune genes, including: …
Did you miss the live broadcast of our latest webinar, The Mysterious World of Macrophages? Access the full recording and watch it any time here. In this webinar, Anne Lodge, Ph.D. answers commonly asked questions about macrophages and explores best practices when it comes to working in both mouse and human models. The Mysterious World…
Includes growth equity investment from Ampersand Capital Partners MEMPHIS, TN and BOTHELL, WA – August 7, 2018 – Key Biologics has completed its merger with Astarte Biologics to create the leading provider of research- and clinical-grade human immune cells, blood products, and related services to the biopharmaceutical industry. In conjunction with the merger, the new entity also received…
Immunology and oncology researchers use leukopaks for a steady supply of effector cells as raw materials for their research and development efforts. Leukopaks are generally collected from healthy donors and shipped fresh overnight, containing between 5 and 20 billion white blood cells depending on the volume of blood processed from the donor during leukapheresis. Leukopaks…
Hot, cold, and in-between. Tumors come in all forms — some better targets for immunotherapy treatment than others. This post will help you learn more about hot tumors, cold tumors, and what researchers are doing to make cold tumors more receptive to immunotherapies. What Are Hot Tumors? Tumors described as “hot” are those that show…
Your diabetes research just got a lot more exciting! Expand your research horizons with our newest antigen-specific T cell line that recognizes a proinsulin peptide. Type 1 diabetes, characterized by the loss of beta cells in the pancreas, affects approximately 1.25 million Americans. That number is expected to rise dramatically to 5 million by 2050. …
Our customers have recently published some exciting research in leading publications. Check out the latest 2019 research featuring our immune cells and products. Effect of comedications and endotoxins on mesenchymal stem cell secretomes, migratory and immunomodulatory capacity Durand et al. examine the effect of immunosuppressive drugs and lipopolysaccharides/endotoxins on the secretory profile, migration towards…
As the basic mechanism that allows our bodies to identify, target, and kill infected or damaged cells, cell-mediated cytotoxicity is an essential function of our immune system and one that scientists continue to explore to develop more advanced immunotherapies. By better understanding the role of T cells and natural killer cells as effector cells and…
We have published several detailed research protocols on our website to help you improve cell performance and optimize your experimental outputs. Two of our protocols have garnered questions from our customers and readers. Namely, what’s the difference between the Recall Antigen Assay and the Antigen-Specific T Cell Assay? In this post, we explain the different…