A Tale of Two Assays: Recall Antigen vs. Antigen-Specific T Cell

We have published several detailed research protocols on our website to help you improve cell performance and optimize your experimental outputs.  Two of our protocols have garnered questions from our customers and readers. Namely, what’s the difference between the Recall Antigen Assay and the Antigen-Specific T Cell Assay?  In this post, we explain the different…

Read more

Researcher Spotlight: Monica Huber

Our scientists bring a wealth of immunology research expertise from diverse backgrounds. With extensive experience in a variety of biologics disciplines, our team is an ideal resource for a wide range of outsource research services. From multiplex assays to flow cytometric analyses, we help you get on with discovery. In this Researcher Spotlight, we introduce…

Read more

Now Available: The Researcher’s Guide to Stem Cells

We field a ton of questions from research scientists related to stem cells. While the use cases for stem cells are vast, many researchers aren’t exactly sure where to start, especially if they’ve never worked with these powerful hematopoietic cells before. That’s why we’ve created a simple guide to answer some of our most frequently…

Read more

Be a Research Champion: Meet Donor 398

Research champions come in many forms. Not all of them wear white coats and goggles. Some have never even stepped foot in a lab, held a pipette, or know what an assay is. These unsung, anonymous research champions are our blood donors. To honor their critical contributions to medical research, we’ll be introducing you to…

Read more

Useful Tools in Immunology: OMIM.org

The Online Mendelian Inheritance in ManⓇ website, or OMIMⓇ, is a publicly available catalog of over 15,000 human genes and all known genetic disorders updated daily by the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins University. Intended for physician and research use, OMIM is a searchable index of clinical features, phenotypes, genes, and more.…

Read more

Upcoming Webinar: The Mysterious World of Macrophages

Though macrophages were first described by Elie Metchnikoff in 1882, there are still plenty of mysteries associated with these versatile immune cells. We field many questions from curious scientists wanting to learn more about macrophages: What Are the Best Methods for Culturing These Cells? What’s the best culture medium?  Do you need to add serum?…

Read more

Now Offering Bone Marrow-Derived Mouse Macrophages

If you’re a frequent buyer of mouse macrophages, you may have noticed a change in our product catalog. Starting in April 2019, we switched from peritoneal macrophages to bone marrow-derived macrophages; a small change for us that can have a big impact on your research. Why the Change? In short, we made the change because…

Read more

Immunology for Non-Immunologists: Cytokine Measurement

What Are Cytokine Measurement Assays? Cytokine measurement assays are sensitive measures for both primary cell assays and purified antigen-specific cultures. Detecting the presence of cytokines — small proteins that are secreted by immune cells to signal an immune or inflammatory response — can help researchers better understand how our bodies respond to invading pathogens. Common…

Read more

Cells in Motion: Recent Patent Applications

Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains Bernett, Matthew et al. “The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an antigen binding domain Fc fusion proteins. In some instances, the antigen binding domain binds to CD8, NKG2A, or…

Read more