The extracellular matrix is a complex combination of non-cellular materials that support biochemical and biomechanical processes in the tissues and organs. Among the components of the extracellular mix are two distinct types of biomolecules: proteoglycans and glycoproteins. Immunology researchers are primarily interested in these biomolecules due to their role in the human tissue processes and…
When I need more information on a protein or antibody, one of the first places I turn to is The Human Protein Atlas. It’s a remarkable open-access collection of all known proteins in human cells, tissues, and organs. When I say remarkable, I mean it. The Human Protein Atlas has amassed detailed information on more…
Macrophages have many applications in immunology research and can produce a wide range of cytokines and chemokines that can influence the immune response in both mouse and human models. We’ve compiled an in-depth guide with our best resources for working with macrophages, the “Big Eaters” of the immune system. You’ll get tips for creating and…
Our contract immunology research team is always looking for a new challenge. So when a customer proposed a project that involved differentiating monocytes into osteoclasts, we said, “Why not!” Fun in the Lab with Monocytes Osteoclasts are macrophages found in bone and are highly specialized myeloid cells that break down and resorb bone tissue, important…
What’s in This Vial? It’s a question we’re happy to hear from inquisitive customers, and one that’s important for all researchers to know the answer to. For years we have been answering customer questions about the pathogen testing that we conduct on our immune cell products and donors, so we’re answering those FAQs here for…
This was our first year attending the Cell Symposia Hallmarks of Cancer event held here in Seattle — and boy was it informative! The event brought together some of the world’s leading cancer researchers and oncologists to share the latest from their research and practices. We got to hear from the likes of Philip Greenburg,…
Have you ever spent weeks or months pursuing a mysterious artifact in your culture only to discover that the cause was a reagent or culture media contaminated with bacterial endotoxin? You’re not alone. Continue reading for a cautionary tale on endotoxin contamination. Detecting a Problem: Clueing in on Endotoxin Contamination We encountered an endotoxin contamination…
New to our ever-expanding immune cell inventory is a CMV-Specific CD4+ T Cell Line, available in large batches of 1–2M cells/vial. Our CMV-specific T cells have been extremely popular among our customers for years, but have only been available as CD8+ cell lines until now. As immunologists, we naturally think of CD8+ T cells when…
MMRF Funds Critical Research Relying on Patients Multiple Myeloma Research Foundation + NexImmune Partnership MMRF’s mission to advance new multiple myeloma therapy into clinical trials for MM patients includes a new formal partnership with NexImmune. A world leader in cancer research, the MMRF’s investment will advance NexImmune’s promising immuno oncology drug candidate NEXI-002 and support…
As a buyer of human and animal immune cell products, you trust that your biomaterials will be handled with care and precision throughout the collection, processing, characterization, and cryopreservation processes. We understand how immensely important cell quality is to the efficacy and timeliness of your research efforts, which is why we are completely transparent with…