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Our cryopreserved peripheral blood mononuclear cells are a great tool for flow cytometry assays. Whether you want to confirm your antibodies are working properly or measure for consistency, our PBMC are the tools you need for quality control. Using PBMC to Test Antibodies Sometimes you might not be sure if your chosen reagent is correctly…
Our resident dendritic cell expert, Benjamin Tjoa, was one of the first scientists in the world to develop dendritic cells for use in cell-based vaccines. Ben has traveled internationally to help labs prepare for developing dendritic cell-based therapies. Monocyte-derived dendritic cells are a hot topic for many of our customers, and Ben has answered countless…
The extracellular matrix is a complex combination of non-cellular materials that support biochemical and biomechanical processes in the tissues and organs. Among the components of the extracellular mix are two distinct types of biomolecules: proteoglycans and glycoproteins. Immunology researchers are primarily interested in these biomolecules due to their role in the human tissue processes and…
When I need more information on a protein or antibody, one of the first places I turn to is The Human Protein Atlas. It’s a remarkable open-access collection of all known proteins in human cells, tissues, and organs. When I say remarkable, I mean it. The Human Protein Atlas has amassed detailed information on more…
Macrophages have many applications in immunology research and can produce a wide range of cytokines and chemokines that can influence the immune response in both mouse and human models. We’ve compiled an in-depth guide with our best resources for working with macrophages, the “Big Eaters” of the immune system. You’ll get tips for creating and…
Our contract immunology research team is always looking for a new challenge. So when a customer proposed a project that involved differentiating monocytes into osteoclasts, we said, “Why not!” Fun in the Lab with Monocytes Osteoclasts are macrophages found in bone and are highly specialized myeloid cells that break down and resorb bone tissue, important…
What’s in This Vial? It’s a question we’re happy to hear from inquisitive customers, and one that’s important for all researchers to know the answer to. For years we have been answering customer questions about the pathogen testing that we conduct on our immune cell products and donors, so we’re answering those FAQs here for…
This was our first year attending the Cell Symposia Hallmarks of Cancer event held here in Seattle — and boy was it informative! The event brought together some of the world’s leading cancer researchers and oncologists to share the latest from their research and practices. We got to hear from the likes of Philip Greenburg,…
Have you ever spent weeks or months pursuing a mysterious artifact in your culture only to discover that the cause was a reagent or culture media contaminated with bacterial endotoxin? You’re not alone. Continue reading for a cautionary tale on endotoxin contamination. Detecting a Problem: Clueing in on Endotoxin Contamination We encountered an endotoxin contamination…
New to our ever-expanding immune cell inventory is a CMV-Specific CD4+ T Cell Line, available in large batches of 1–2M cells/vial. Our CMV-specific T cells have been extremely popular among our customers for years, but have only been available as CD8+ cell lines until now. As immunologists, we naturally think of CD8+ T cells when…