Comparing Natural and Induced T Regulatory Cells

When buying T regulatory cells for autoimmune or immunotherapy research, you have two options: natural T regulatory cells or induced T regulatory cells. The main difference between the two is quite clear. Induced Tregs are differentiated in the lab outside of the thymus, while natural Tregs come directly from the donor’s body. But there are…

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Researcher Spotlight: Benjamin Tjoa

Our scientists bring a wealth of immunology research expertise from diverse backgrounds. With extensive experience in a variety of biologics disciplines, our team is an ideal resource for a wide range of outsource research services. From multiplex assays to flow cytometric analyses, we help you get on with discovery. In this researcher spotlight, we introduce…

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5 Benefits of Testing with Pooled PBMC

1. Eliminate Costly LAL & Rabbit Testing Because their blood clots at the presence of bacterial endotoxins, lysate of horseshoe crab blood (Limulus amoebocyte lysate, LAL) has been used since the 1960s to test pharmaceuticals for substances that can cause fever. The rabbit pyrogen test was more commonly used before the 1960s but is still…

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Ask a Scientist:How Do I Decode the HLA System?

Despite being central to adaptive immunity and transplantation, the genetic locus that encodes Human Leukocyte Antigens (HLA) can be confusing to scientists who don’t specialize in it. HLA Background The molecules that belong to the HLA system were first defined using antibodies: the class I antigens (A, B and C) and the class II antigen…

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Functional Testing for T Cell and PBMC Quality Control

Proper testing of antigen specific T cells and PBMC is essential to ensure antigen specificity and cell functionality. Whether you’re purchasing human cells for research from a supplier or preparing your own antigen specific T cells or PBMC for experimentation, it’s important to perform the appropriate tests beforehand. We always test our antigen specific T…

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