Announcing a New List of SLE Donors

We are happy to announce the availability of an expanded list of SLE donors in our immune cell catalog. In partnership with Physicians Plasma Alliance, we have isolated PBMC, purified CD4+ T cells, and purified CD8+ T cells from donors with SLE (Systemic Lupus Erythematosis). Although Physicians Plasma Alliance is located in Tennessee, we are…

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Case Study: How Fresh Are Your PBMC?

When ordering human or animal immune cells for research, it’s important to know as many details about the products as possible. That’s why we provide a detailed Certificate of Analysis for each cell product we offer. But beyond knowing information about the cells and donors, you should also inquire about your supplier’s collection and processing…

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Mouse Bone Marrow: Your Multipurpose Cells

Mouse bone marrow cells are a multipurpose resource for conversion to several other useful cell types. Mouse bone marrow contains hematopoietic stem cells, which makes it an excellent starting point for deriving cells of various hematopoietic lineages.   Converting Mouse Bone Marrow to Other Cells: 3 Examples 1) Bone Marrow to Macrophages When cultured in…

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Cells in Motion: Immune and Cancer Cells

At the 2017 ASCO-SITC Clinical Immuno-Oncology Symposium in Orlando, researchers from Biodesix presented a poster featuring our cells. The poster, “Development of ddPCR blood-based diagnostic tests that simultaneously measure mRNA expression from immune and cancer cells,” demonstrates how Biodesix developed sensitive and specific methods that can be applied in gene expression studies in blood. These…

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2017 Pipeline Report: Trends & Projections in Biopharma

Complexity is the operative word in Pharm Exec’s 2017 Pipeline Report. Complex diseases are driving the development of new and innovative therapies while the market adjusts to manufacturing challenges and increasing drug costs. We’ve recapped some of the main topics in the report, including CAR-T therapies, combination treatments and nonalcoholic steatohepatitis (NASH), among others.  …

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After SLAS2017: Inspired to Innovate

I’m on my way back from Washington, D.C. where our chief scientist, Ben Tjoa, and I were exhibiting at SLAS2017 this week. I don’t always leave events feeling this inspired, but SLAS put on a fantastic event. We had some great discussions with colleagues, shared ideas with peers and learned about new innovations in the…

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Using the Epstein-Barr Virus to Study the Immune System

The Epstein-Barr virus (EBV) is one of the most prevalent infections, found in about 95% of the adult population. EBV is a lifelong infection with ties to many diseases. Although infected individuals often build adaptive immunity to EBV and are asymptomatic, EBV is associated with infectious mononucleosis, several types of cancer such as Hodgkin’s lymphoma,…

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Cells in Motion: Macrophage Research

Macrophages play an important role in immunology, cancer, and inflammatory research. Two recent publications featured our cells to study the various effects of macrophages on killing breast cancer cells and impacting reproductive health, respectively.   Macrophage-mediated Trogocytosis Leads to Death of Antibody-opsonized Tumor Cells Velmurugan, et al. found that trogocytosis was effective in killing HER2-overexpressing…

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