Nitric oxide (NO) was the first gas shown to impact normal bodily functions, including the immune system, earning it the Science Molecule of the Year award in 1992. In addition to the immune system, small amounts of NO in the body have also demonstrated effects on blood pressure, long-term memory, the nervous system, and several…
Natural Killer cells, as their name suggests, are the prime example of cytotoxic cells. However, NK cells aren’t your only option for cytotoxicity. Activated CD8+ T cells are the classic example of cytotoxic T cells, but CD4+ T cells have also been demonstrated to kill their targets. In this post, we’ll dive into the different…
Our customers know that we take great pride in the quality and functionality of all our cell products. When it comes to demonstrating the functionality of peripheral blood mononuclear cells (PBMC), there is no industry-standard protocol. We developed a recall antigen assay as an internal test of our PBMC functionality in order to demonstrate the…
What’s better than saving time and making your ordering process easier? Getting free shipping! When you create a new online account with us, you’ll get free shipping on your first order. It’s that simple! Here’s how it works: 1. If you don’t already have an online account, create one in under a minute! No credit…
The pharmaceutical industry is constantly evolving and making headlines. Here are a few stories in the news recently. Gilead Purchases Kite Pharma for $11.9 Billion Set to close in Q4 2017, Gilead’s acquisition is the culmination of an effort to diversify their pipeline from hepatitis medications and become a player in the development of personalized…
We’re often asked about naïve T cells and memory T cells; specifically if we have both types in our inventory. We do carry both types of CD4+ T cells from multiple donors, and savvy researchers know when to ask for each. Naïve T cells are essential components of the immune system that enable the body…
We’re dedicated to providing quality immune cell products. Your research and innovations depend on our cells working as described. We’ve always stood behind our products, but wanted to make our dedication to quality even more transparent in our new guarantee: If your order does not match the specifications on the Certificate of Analysis, we will…
We may not have to wait much longer for the first FDA-approved CAR-T cell therapy. The Food and Drug Administration’s Oncologic Drugs Advisory Committee (ODAC) recently recommended Novartis’ CTL019 CAR-T cell therapy for FDA approval by unanimous decision, a major step forward for the groundbreaking biologic. CTL019, indicated for pediatric and young adult r/r B…
When you buy immune cell products, you want a supplier that is committed to providing quality cells using a sustainable business model. If you find a cell type or donor you need, you should be able to order the same product again and again until your research needs are met. We believe in sustainable business…
New research on PD-1 and PD-L1 inhibitors is raising questions on the positive and negative effects of popular cancer treatments, calling for further studies. PD-L1 Inhibits Chronic Pain in Mice Ru-Rong Ji (Duke University) and Yu-Qiu Zhang (Fudan University) have shown that PD-L1 can lessen acute and chronic pain when injected into mice. The team…