When ordering human or animal immune cells for research, it’s important to know as many details about the products as possible. That’s why we provide a detailed Certificate of Analysis for each cell product we offer. But beyond knowing information about the cells and donors, you should also inquire about your supplier’s collection and processing…
Mouse bone marrow cells are a multipurpose resource for conversion to several other useful cell types. Mouse bone marrow contains hematopoietic stem cells, which makes it an excellent starting point for deriving cells of various hematopoietic lineages. Converting Mouse Bone Marrow to Other Cells: 3 Examples 1) Bone Marrow to Macrophages When cultured in…
At the 2017 ASCO-SITC Clinical Immuno-Oncology Symposium in Orlando, researchers from Biodesix presented a poster featuring our cells. The poster, “Development of ddPCR blood-based diagnostic tests that simultaneously measure mRNA expression from immune and cancer cells,” demonstrates how Biodesix developed sensitive and specific methods that can be applied in gene expression studies in blood. These…
Monocytes and macrophages are very closely related cells with a few important distinctions and different use cases. Put simply, monocytes are macrophages in the blood; macrophages are monocytes in tissue. Understanding the Difference Monocytes are the largest type of white blood cells and play an important role in the adaptive immunity process. Monocytes typically…
Complexity is the operative word in Pharm Exec’s 2017 Pipeline Report. Complex diseases are driving the development of new and innovative therapies while the market adjusts to manufacturing challenges and increasing drug costs. We’ve recapped some of the main topics in the report, including CAR-T therapies, combination treatments and nonalcoholic steatohepatitis (NASH), among others. …
CMV antigens and CMV peptides are both great tools for studying the implications of the human cytomegalovirus (CMV), which infects nearly 1/3 of children before the age of five and more than half of adults in the U.S. Although CMV-infected individuals are often asymptomatic, the virus does pose a serious threat to individuals with weakened…
I’m on my way back from Washington, D.C. where our chief scientist, Ben Tjoa, and I were exhibiting at SLAS2017 this week. I don’t always leave events feeling this inspired, but SLAS put on a fantastic event. We had some great discussions with colleagues, shared ideas with peers and learned about new innovations in the…
The Epstein-Barr virus (EBV) is one of the most prevalent infections, found in about 95% of the adult population. EBV is a lifelong infection with ties to many diseases. Although infected individuals often build adaptive immunity to EBV and are asymptomatic, EBV is associated with infectious mononucleosis, several types of cancer such as Hodgkin’s lymphoma,…
Macrophages play an important role in immunology, cancer, and inflammatory research. Two recent publications featured our cells to study the various effects of macrophages on killing breast cancer cells and impacting reproductive health, respectively. Macrophage-mediated Trogocytosis Leads to Death of Antibody-opsonized Tumor Cells Velmurugan, et al. found that trogocytosis was effective in killing HER2-overexpressing…
SLAS2017 will head to the Walter E. Washington Convention Center in Washington, D.C. February 4–8, 2017. The area surrounding the Convention Center offers a variety of ethnic foods, local coffee shops, and unique dining experiences. In preparation for your stay, we’ve compiled a list of some of the top-rated local restaurants and coffee shops near…
Cellero to Join Charles River
Together, we deliver the most reliable biomaterials and services to advance the discovery and development of new treatments and cures.
