Our new series, Immunology for Non-Immunologists, will focus on key concepts to help scientists and researchers without extensive immunology backgrounds understand the functions and use cases for our immune cell products. Our last Immunology for Non-Immunologists post described how T cells recognize peptides bound to MHC molecules, and how changes to the peptide or MHC…
Need research help? We’re offering a limited number of free research consultations with one of our lead cellular immunologists! Take advantage of this opportunity to ask a scientist about your current research hurdles, get help setting up an experiment, or review and interpret your results. Immunology and Inflammation Research Expertise We specialize in contract research…
Donating blood is a simple way to give a powerful gift. According to the American Red Cross, patients need around 36,000 units of red blood cells, 7,000 units of platelets, and 10,000 units of plasma every single day in the U.S. The only way patients can get the treatment they need is if altruistic people…
About 6.8 million Americans donate blood annually, according to the American Red Cross. From transfusions to research, donated blood has multiple purposes — all of which help other people. If you are about to join the millions of donors, understanding what to expect and how to care for yourself following the donation process is absolutely…
Have you struggled to replicate the research findings of another scientist? Or failed to reproduce your own research results? You’re definitely not alone. According to Nature, over 70% of scientists have failed to reproduce the results of another scientist and more than 50% have failed to reproduce their own results. While there are no industry-standard…
The success with chimeric antigen receptor T cells (CAR-T cells) has reinvigorated interest in T cells and their natural recognition of target antigens. Many researchers are interested in antigen-specific T cells for developing T cell receptor-based therapies, which was a big topic at the ASCO Annual Meeting last month. With so much demand for antigen-specific…
Macrophages and myeloid dendritic cells can be proinflammatory or express suppressive, anti-inflammatory characteristics. One characteristic that is part of the proinflammatory phenotype is the expression of inducible nitric oxide synthetase (iNOS), which can be evaluated by measuring production of nitric oxide using our all-inclusive Nitric Oxide Assay Kit. This easy-to-use NO Kit can give rapid…
Researchers have been busy using Cellero cells! Here are a few articles that were recently published in leading publications. Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages Velmurugan et al. explore the identification of a vacuolar compartment and the implications for understanding the subcellular trafficking process. Cellero…
Carboxyfluorescein diacetate succinimidyl ester, or CFDA-SE, is a fluorescent dye used to stain and label cells to track their division. CFDA-SE is cell permeable, meaning it can cross the cell membrane and stay there for long periods of time. Once inside the cell, CFDA-SE reacts with amine groups on proteins to create a stable fluorescent…
Our new series, Immunology for Non-Immunologists, will focus on key concepts to help scientists and researchers without extensive immunology backgrounds understand the functions and use cases for our immune cell products. This post focuses on the T cell antigen recognition process. If you have other questions about using our products in your lab, just ask…