Have you struggled to replicate the research findings of another scientist? Or failed to reproduce your own research results? You’re definitely not alone. According to Nature, over 70% of scientists have failed to reproduce the results of another scientist and more than 50% have failed to reproduce their own results. While there are no industry-standard…
The success with chimeric antigen receptor T cells (CAR-T cells) has reinvigorated interest in T cells and their natural recognition of target antigens. Many researchers are interested in antigen-specific T cells for developing T cell receptor-based therapies, which was a big topic at the ASCO Annual Meeting last month. With so much demand for antigen-specific…
Macrophages and myeloid dendritic cells can be proinflammatory or express suppressive, anti-inflammatory characteristics. One characteristic that is part of the proinflammatory phenotype is the expression of inducible nitric oxide synthetase (iNOS), which can be evaluated by measuring production of nitric oxide using our all-inclusive Nitric Oxide Assay Kit. This easy-to-use NO Kit can give rapid…
Researchers have been busy using Cellero cells! Here are a few articles that were recently published in leading publications. Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages Velmurugan et al. explore the identification of a vacuolar compartment and the implications for understanding the subcellular trafficking process. Cellero…
Carboxyfluorescein diacetate succinimidyl ester, or CFDA-SE, is a fluorescent dye used to stain and label cells to track their division. CFDA-SE is cell permeable, meaning it can cross the cell membrane and stay there for long periods of time. Once inside the cell, CFDA-SE reacts with amine groups on proteins to create a stable fluorescent…
Our new series, Immunology for Non-Immunologists, will focus on key concepts to help scientists and researchers without extensive immunology backgrounds understand the functions and use cases for our immune cell products. This post focuses on the T cell antigen recognition process. If you have other questions about using our products in your lab, just ask…
Breakthroughs in personalized medicine start with high-quality, well-characterized immune cell products. Making such products widely available to researchers in fields like immunology, inflammation, and vaccine development was the catalyst to founding Astarte Biologics (now Cellero) over 14 years ago. Since recognizing a need in the industry and launching our company with human PBMC and T…
Years ago, we used to be annoyed at the abundance of platelets clogging up the cell suspensions in our leukapheresis products. What were we going to do with all those leftover platelets? Instead of washing them out of our suspensions and discarding them, we realized we could put them to better use in research labs…
Also announces installation of Asymptote VIA Quad Freeze controlled-rate freezer MEMPHIS, TN, and MONTREAL QC, May 14, 2018 – Key Biologics LLC , a provider of biological raw materials and services for manufacturing cell-based therapeutics, today announced the availability of fresh and frozen whole leukaphereses from patients with hematologic malignancies; Multiple Myeloma, Non-Hodgkin Lymphoma, Chronic…
We left PEGS 2018 feeling energized from many conversations with like-minded scientists around research and the advancements in protein drug development. For those of you who were at PEGS, I hope you departed feeling as inspired as we were. For those of you who missed it, here are our top three discussion topics. The Importance…