Transferring immune cell products from the freezer to shipment containers and eventually to the end user’s freezer involves big temperature swings and potential stress on the cells. With many years of experience as an immune cell provider shipping products worldwide, we have perfected our temperature control and shipping processes.

Our standard shipping methods will mitigate stress on your products. We have tested our containers to ensure they will maintain dry ice temperatures for 4 days. To further limit temperature changes during the packing process, we hold our vials in liquid nitrogen while assembling shipments.

We ship our cells on dry ice at approximately –79°C. We can also ship cells in liquid nitrogen vapor, but because it is much more expensive, we only recommend this option if absolutely necessary.

In addition to shipping conditions, we also strategically time shipments to further mitigate cell stress. We usually ship orders upon receipt when in stock, so you can expect your shipment the next day. If weather or other shipping delays are predicted, we will hold your shipment to prevent damage in transit.

 

Extra Precautions to Ensure Cell Viability During Transit

If you are particularly worried about the shipping conditions of your high-value order, there are extra risk mitigation precautions we can take together to ensure the viability of your product.

1. Consider Dry Shippers

Dry shippers can hold temperatures at liquid nitrogen vapor levels while also complying with transportation regulations. Due to the increased container size and weight, we do not recommend this method for small purchases.

2. Quickly Transfer Cells to Liquid Nitrogen Storage

For shipments received on dry ice, it is critical to return the cells to liquid nitrogen storage as quickly as possible. We do our part by shipping products to minimize transit time and keeping an eye on weather conditions or other possible transit delays. As the receiver, be sure you open the container and transfer the cells into permanent storage without delay.

If you do not have liquid nitrogen storage, store cells at –80°C and plan to use them as soon as possible.

RELATED: How to Thaw, Handle & Store Frozen Cells

 

3. Limit Freezer Access and Plan Accordingly

If you purchase a large batch of vials, consider storing them in multiple locations, if possible. Continually opening and closing a freezer to remove one or two vials exposes all products in the freezer to transient increases and decreases in temperature.

While this may seem innocuous, even small temperature changes over time will impact cell viability and functionality. This can become problematic for a larger batch of vials stored in the same location and used vial-by-vial over a few months.

 

Working Together to Ensure Cell Quality

Being a conscious consumer and planning for the proper handling and storage resources will go a long way toward maintaining the viability and functionality of your immune cell purchases. Be sure to order the appropriate quantity of products based on your needs and follow best practices for receiving, handling, storing, and thawing cells.

Have more specific questions about cell shipping and handling?

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