Ask A Scientist: What Antigens Can Stimulate IFNγ Producing CD8+ T Cells?

A curious researcher recently asked us to suggest suitable antigens that could stimulate IFNγ producing CD8+ T cells.  The short answer: Virus proteins.  But as with anything in immunology and virology, there is a longer, more complicated explanation as well.    Protein Antigens vs. Peptide Antigens CD8+ T cells normally recognize antigens that are produced…