Dr. Lodge is the Chief Science and Innovation Officer at Cellero. She has a strong background in cell-based therapeutics and immunology, including a Ph.D. in Cell and Molecular Biology from the University of Vermont and a postdoctoral fellowship with the Multiple Sclerosis Society studying the role of T cells in the disease process. Learn more about Dr. Lodge.

Immunology for Non-Immunologists: Innate vs. Adaptive Immunity

Scientific studies directly or indirectly involving human immunity require an understanding of both sides of the complex system. Even the development of an adaptive antigen-specific cell-based therapy requires components of the innate immune system that work in concert with the adaptive cells. If you don’t work primarily in immunology, this post will give you a…

Ask A Scientist: Progenitor vs. CD34+ Cells

Progenitor cells and CD34+ cells are often referred to interchangeably as stem cells. While this oversimplification is technically correct, there are many distinctions between the origins, functions, and uses of progenitor cells and CD34+ cells. What is the Difference Between Progenitor and CD34+ Cells? Despite their many similarities, the most significant difference between the two…

Immunology for Non-Immunologists: Proliferation Assays

What are Proliferation Assays? Proliferation assays are a category of immune cell activation tests designed to measure cell division. Proliferation assays are some of the most commonly used measures of immune cell activation. Examples include: Tritiated Thymidine Incorporation (3H-thymidine Incorporation) Bromodeoxyuridine Incorporation (BrdU) Tetrazolium Dyes CFSE Dye Reduction CellTiter-Glo® Learn more about each method below.…