Use of Nitric Oxide to Characterize Macrophages and Dendritic Cells

Macrophages and myeloid dendritic cells can be proinflammatory or express suppressive, anti-inflammatory characteristics. One characteristic that is part of the proinflammatory phenotype is the expression of inducible nitric oxide synthetase (iNOS), which can be evaluated by measuring production of nitric oxide using our all-inclusive Nitric Oxide Assay Kit. This easy-to-use NO Kit can give rapid…

Cells in Motion: Cellero Cells Featured in Recent Publications

Researchers have been busy using Cellero cells! Here are a few articles that were recently published in leading publications. Phagocytosis of antibody‐opsonized tumor cells leads to the formation of a discrete vacuolar compartment in macrophages Velmurugan et al. explore the identification of a vacuolar compartment and the implications for understanding the subcellular trafficking process. Cellero…

Using CFDA-SE in Your Lab

Carboxyfluorescein diacetate succinimidyl ester, or CFDA-SE, is a fluorescent dye used to stain and label cells to track their division. CFDA-SE is cell permeable, meaning it can cross the cell membrane and stay there for long periods of time. Once inside the cell, CFDA-SE reacts with amine groups on proteins to create a stable fluorescent…