Ask a Scientist:How Do I Decode the HLA System?
Despite being central to adaptive immunity and transplantation, the genetic locus that encodes Human Leukocyte Antigens (HLA) can be confusing to scientists who don’t specialize in it. HLA Background The molecules that belong to the HLA system were first defined using antibodies: the class I antigens (A, B and C) and the class II antigen…